![]() This important article reveals how far we have come in our understanding of viral hepatitis - particularly non-A, non-B hepatitis - in just the last 25 years. Purcell RH, Alter HJ, Dienstag JL: Non-A, non-B hepatitis. Within less than two decades of the discovery of HEV, its epidemiology has been described, serologic tests have been developed, and a candidate vaccine has been evaluated in clinical trials. The characterization of the major types of viral hepatitis during the last 20 years illustrates how modern genetic technology has revolutionized research in infectious diseases. A recombinant HEV vaccine is currently in phase III clinical trials. Recent studies indicate that hepatitis E may be a zoonotic disease, with pigs and possibly rats serving as reservoirs for human infection. ![]() Although usually asymptomatic, HEV infection can cause fulminant hepatitis. Fecal contamination of drinking water is the most common mode of spread. ![]() HEV transmission is highly endemic in Asia, the Middle East, and Africa. The novel hepatitis E virus (HEV) subsequently was cloned in 1990 and the genome sequenced. By practicing good hygiene, avoiding contaminated food and water, and getting vaccinated, you can protect yourself and reduce the risk of Hepatitis A infection.The infectious agent causing epidemic non-A, non-B hepatitis was identified in 1983 from a human challenge experiment. Understanding how Hepatitis A is transmitted in adults is crucial for taking preventive measures. Q: Who should get vaccinated against Hepatitis A?Ī: Vaccination against Hepatitis A is recommended for individuals at higher risk, including travelers to areas with high Hepatitis A prevalence, men who have sex with men, and individuals with chronic liver disease. Q: Is there a cure for Hepatitis A?Ī: While there is no specific cure for Hepatitis A, most people recover completely without any long-term liver damage. Q: How long is a person with Hepatitis A contagious?Ī: A person with Hepatitis A is most contagious from two weeks before symptoms appear to one week after the onset of jaundice.
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